Multicentre Uk Experience of Sex Cord Stromal Tumours

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Ovary: Sex cord-stromal tumors

There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterised by multiple gastrointestinal hamartomatous polyps, increased risk of various neoplasms, and melanocytic macules of the lips, buccal mucosa...

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Value of A103 (melan-A) immunostaining in the diVerential diagnosis of ovarian sex cord stromal tumours

Aims—To assess A103 (melan-A) immunoreactivity in a range of ovarian sex cord stromal tumours and to evaluate it for the diVerential diagnosis of other neoplasms. Methods—ParaYn embedded tissue sections from 45 sex cord stromal tumours and 44 potential histological mimics were examined immunohistochemically using the antibody A103. The sex cord stromal group included 21 adult granulosa cell tum...

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Value of A103 (melan-A) immunostaining in the differential diagnosis of ovarian sex cord stromal tumours.

AIMS To assess A103 (melan-A) immunoreactivity in a range of ovarian sex cord stromal tumours and to evaluate it for the differential diagnosis of other neoplasms. METHODS Paraffin embedded tissue sections from 45 sex cord stromal tumours and 44 potential histological mimics were examined immunohistochemically using the antibody A103. The sex cord stromal group included 21 adult granulosa cel...

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Uterine tumours resembling ovarian sex cord tumours: a case report

BACKGROUND Endometrial stromal tumours with sex-cord-like elements were first described by Clement and Scully in 1976. The recent World Health Organisation classification 2003 recognises low grade stromal sarcoma and undifferentiated endometrial sarcoma. CASE PRESENTATION A 62-year-old caucasian woman presented with recurrent postmenopausal bleeding. She underwent a diagnostic hysteroscopy wh...

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One of the unusual variant of ovarian tumor is sex cord stromal tumor with annular tubules (SCTAT). The recurrence in case of malignant ovarian SCTAT ranges from 3mo to 20yr. This report describes the case of recurrence of SCTAT in a 35yr old woman after 4yr of hysterectomy with bilateral salphingo-Oopherectomy. Microscopic examination revealed features of SCTAT. Because of its unusual behavior...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2014

ISSN: 0923-7534

DOI: 10.1093/annonc/mdu337.54